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Complications of percutaneous thrombin injection in patients with postcatheterization femoral pseudoaneurysm
Author(s) -
Kurzawski Jacek,
Sadowski Marcin,
JanionSadowska Agnieszka
Publication year - 2015
Publication title -
journal of clinical ultrasound
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.272
H-Index - 61
eISSN - 1097-0096
pISSN - 0091-2751
DOI - 10.1002/jcu.22274
Subject(s) - medicine , femoral artery , embolization , percutaneous , pseudoaneurysm , embolism , thrombin , lumen (anatomy) , radiology , surgery , aneurysm , ultrasound , platelet
Purpose To study the complications of ultrasound‐guided thrombin injection of pseudo‐aneurysms occurring after interventional cardiovascular procedures. Method We prospectively studied 353 patients who developed post‐catheterization femoral artery pseudo‐aneurysms and were treated with ultrasound‐guided thrombin injection. Results Arterial micro‐embolization occurred in 53 patients (15%) and pulmonary embolism in 1 patient (0.3%). None of the patients developed significant peripheral arterial embolism. The length of the communicating channel between the arterial lumen and the pseudo‐aneurysm was inversely correlated with the risk of embolization ( p < 0.0001). A 4.6 mm increase in channel length decreased the odds of embolization by 14%, and patients with a channel less than 2 mm long were at greater risk. Repeated thrombin injection also increased the risk of embolization ( p = 0.02). Conclusion Thrombin injection for the treatment of post‐catheterization femoral pseudo‐aneurysm is feasible and safe, but it must be performed with caution, especially when the sac is directly communicating with the artery, or when success cannot be achieved with a single injection. © 2015 Wiley Periodicals, Inc. J Clin Ultrasound 44 :188–195, 2016;