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Diagnostic usefulness of quantitative tissue velocity imaging and anatomic M‐mode echocardiography for coronary artery diseases: A pilot study
Author(s) -
Chen Shaoqi,
Chen Xiaoxia,
Zheng Baoqun
Publication year - 2014
Publication title -
journal of clinical ultrasound
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.272
H-Index - 61
eISSN - 1097-0096
pISSN - 0091-2751
DOI - 10.1002/jcu.22218
Subject(s) - medicine , cardiology , coronary artery disease , ejection fraction , thickening , receiver operating characteristic , artery , stenosis , coronary angiography , radiology , nuclear medicine , myocardial infarction , heart failure , chemistry , polymer science
Background and objective To explore the potential clinical usefulness and determine optimal diagnostic criteria of quantitative tissue velocity imaging and anatomic M‐mode echocardiography in patients with coronary artery disease (CAD). Methods We used quantitative tissue velocity imaging for the measurement of systolic myocardial velocity, and anatomic M‐mode echocardiography for the measurement of ventricular wall‐thickening fraction in 44 subjects with suspected CAD. Subjects were classified as patients if coronary angiography demonstrated a stenosis ≥50%, and as controls if it was strictly normal. The diagnostic criteria, sensitivity, and specificity were assessed by receiver‐operator curves. Results Controls had greater mean systolic myocardial velocity and ventricular wall‐thickening fraction in the basal (6.59 ± 1.25 cm/s and 0.44 ± 0.05) and mid segment (5.23 ± 0.93 cm/s and 0.43 ± 0.04) than patients (5.02 ± 1.17 cm/s and 0.29 ± 0.04, 3.27 ± 1.29 cm/s and 0.29 ± 0.04, respectively, p < 0.001). Mid‐segment ventricular wall‐thickening fraction offered 95% sensitivity (95% CI 88.7% to 98.4%), and 98.3% specificity (95% CI 90.9% to 1.0) with an optimal cut‐off point of 0.349, yielding better results than systolic myocardial velocity, which provided 83% sensitivity (95% CI 74.2% to 89.8%), 90% specificity (95% CI 79.5% to 96.2%), and optimal cut‐off point 4.47. The combination of systolic myocardial velocity and ventricular wall‐thickening fraction offered 97% sensitivity (95% CI 91.5% to 99.4%) Conclusions Mid‐segment ventricular wall‐thickening fraction might be suitable for the evaluation of patients with CAD. © 2014 Wiley Periodicals, Inc. J Clin Ultrasound 43 :346–352, 2015