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Changes in maternal posterior and anterior cerebral artery flow velocity during pregnancy and postpartum—A longitudinal study
Author(s) -
Veen Teelkien R.,
Haeri Sina,
SangiHaghpeykar Haleh,
Belfort Michael A.
Publication year - 2013
Publication title -
journal of clinical ultrasound
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.272
H-Index - 61
eISSN - 1097-0096
pISSN - 0091-2751
DOI - 10.1002/jcu.22091
Subject(s) - medicine , anterior cerebral artery , posterior cerebral artery , middle cerebral artery , pregnancy , cardiology , transcranial doppler , diastole , ultrasound , gestation , cerebral arteries , blood flow , hemodynamics , postpartum period , cerebral blood flow , percentile , obstetrics , blood pressure , radiology , ischemia , biology , genetics , statistics , mathematics
Background To evaluate the normal range of blood flow velocity in the maternal anterior (ACA) and posterior cerebral arteries (PCA) along the normal pregnancy and postpartum period. Methods Transcranial Doppler ultrasound was used to measure the systolic, diastolic, and mean blood velocities in the ACA and PCA during normal gestation. The resistance and pulsatility indices were calculated. Data were analyzed using multilevel modeling, incorporating random effects models, to construct mean and percentile curves. Results We performed 355 measurements on 59 patients, which showed that systolic and mean velocity in the ACA decreased, whereas diastolic velocity increased in the PCA during normal pregnancy. Resistance and pulsatility indices in both vessels increased to a maximum in the second trimester, decreased during the third trimester, and increased during the postpartum period. Conclusions This study provides normative data for ACA and PCA velocity and indices during pregnancy and postpartum, demonstrating changes in velocity that suggest a shift of cerebral blood flow from the anterior to the posterior cerebral circulation. © 2013 Wiley Periodicals, Inc. J Clin Ultrasound 41 :532–537, 2013.