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First trimester transabdominal chorionic villus sampling—does the needle matter?
Author(s) -
Wax Joseph R.,
Cartin Angelina,
Chard Renée,
Carpenter Molly,
Pinette Michael G.
Publication year - 2012
Publication title -
journal of clinical ultrasound
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.272
H-Index - 61
eISSN - 1097-0096
pISSN - 0091-2751
DOI - 10.1002/jcu.21925
Subject(s) - medicine , chorionic villus sampling , amniocentesis , gestational age , obstetrics , gynecology , pregnancy , gestation , first trimester , fetus , prenatal diagnosis , biology , genetics
Purpose To compare first‐trimester transabdominal chorionic villus samples (TA‐CVS) when obtained by 20‐gauge amniocentesis versus lancet needles. Methods This is a retrospective study of all women with viable singleton pregnancies undergoing TA‐CVS from 01/01/2009 to 03/31/2011. All CVS were performed by a single operator using a freehand technique and amniocentesis needles from 01/01/2009 to 08/31/2010 and lancet needles from 09/01/2010 to 03/31/2011. All samples were processed by the same laboratory. Results There were no differences between groups regarding maternal age, weight, gestational age at CVS, indication for CVS, uterine position, or placental location. Lancet needles were associated with significantly larger samples (median 18 [range 3–40] versus 7 [range 1–33] mg, p < 0.0001), more successful in situ hybridization (96% versus 74.2%, p = 0.03), and faster result reporting (median 7 [range 5–12] versus 9 [range 6–26] days, p = 0.002). Conclusions Needle type may be clinically important when selecting 20‐gauge TA‐CVS needles. © 2012 Wiley Periodicals, Inc. J Clin Ultrasound 40:385–388, 2012