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Sirenomelia apus after trimethoprim exposure: First‐trimester ultrasound diagnosis—a case report
Author(s) -
Dosedla Erik,
Kalafusová Michaela,
Calda Pavel
Publication year - 2012
Publication title -
journal of clinical ultrasound
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.272
H-Index - 61
eISSN - 1097-0096
pISSN - 0091-2751
DOI - 10.1002/jcu.21915
Subject(s) - medicine , ultrasound , fetus , umbilical cord , third trimester , obstetrics , pregnancy , radiology , anatomy , biology , genetics
We report the early prenatal ultrasound diagnosis of sirenomelia apus at 12+4 weeks in a patient with trimethoprim exposure in the vulnerable period. First‐trimester scan revealed a malformed fetus with one femur, one small tibia, no feet, intraabdominal unilocular cystic structure, and two‐vessel umbilical cord with allantoic cyst. Ultrasound visualization with two/three/four‐dimensions was helpful in the process of parental counseling. © 2012 Wiley Periodicals, Inc. J Clin Ultrasound, 2012;