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Contrast‐enhanced sonography‐guided radiofrequency ablation for the local recurrence of previously treated hepatocellular carcinoma undetected by b‐mode sonography
Author(s) -
Miyamoto Noriyuki,
Hiramatsu Kazuhide,
Tsuchiya Kazuhiko,
Sato Yukihiko
Publication year - 2010
Publication title -
journal of clinical ultrasound
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.272
H-Index - 61
eISSN - 1097-0096
pISSN - 0091-2751
DOI - 10.1002/jcu.20720
Subject(s) - medicine , hepatocellular carcinoma , radiology , radiofrequency ablation , contrast enhanced ultrasound , percutaneous , ultrasound , ablation , concordance
Background. The purpose of this study was to assess the usefulness of contrast‐enhanced sonography (CEUS) with Sonazoid to demonstrate local recurrence of hepatocellular carcinoma previously treated with radiofrequency ablation (RFA) and not seen on conventional sonography, prior to repeat RFA. Methods. This study included 16 cirrhotic patients with 17 cases of hypervascular locally recurrent hepatocellular carcinoma found by contrast‐enhanced multidetector row CT (MDCT) but not seen on noncontrast sonography. We used Kupffer‐phase imaging and vascular‐phase imaging after re‐injection. The morphologic patterns of local recurrence detected on CEUS were compared with those on MDCT. We performed repeat RFA guided by CEUS using Kupffer‐phase imaging after re‐injection. Results. We were able to detect on CEUS the location of all local recurrences with positive enhancement after re‐injection. The morphologic patterns of local recurrence on CEUS were in concordance with those found on MDCT in all lesions. Repeat percutaneous RFA was successfully performed in all lesions. Conclusions. The CEUS appearance of local recurrences correlated well with those on MDCT. A wider use of CEUS to guide repeat of percutaneous RFA may be possible with Sonazoid. © 2010 Wiley Periodicals, Inc. J Clin Ultrasound 38:339‐345, 2010