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Effects of diffuse fatty infiltration of the liver on portal vein flow hemodynamics
Author(s) -
Balci Ali,
Karazincir Sinem,
Sumbas Haldun,
Oter Yasemin,
Egilmez Ertugrul,
Inandi Tacettin
Publication year - 2008
Publication title -
journal of clinical ultrasound
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.272
H-Index - 61
eISSN - 1097-0096
pISSN - 0091-2751
DOI - 10.1002/jcu.20440
Subject(s) - medicine , infiltration (hvac) , ultrasound , fatty liver , blood flow , portal vein , hemodynamics , color doppler , nuclear medicine , gastroenterology , cardiology , ultrasonography , radiology , physics , disease , thermodynamics
Purpose To investigate the effects of various degrees of diffuse fatty infiltration of the liver on portal vein blood flow with Doppler sonography. Methods One hundred forty subjects were examined with color and spectral Doppler sonography. The subjects were divided into 4 groups of 35 subjects each according to the degree (normal, grade 1, grade 2 and grade 3) of hepatic fatty infiltration assessed on gray‐scale images. The portal vein pulsatility index (VPI) and time‐averaged mean flow velocity (MFV) were calculated for each subject. VPI was calculated as (peak maximum velocity − peak minimum velocity) / peak maximum velocity. Results VPI and MFV values were, respectively, 0.32 ± 0.06 and 16.8 ± 2.6 cm/second in the normal group, 0.27 ± 0.07 and 14.2 ± 2.2 cm/second in the group with grade 1 fatty infiltration, 0.22 ± 0.06 and 12.2 ± 1.8 cm/second in the group with grade 2 fatty infiltration, and 0.18 ± 0.04 and 10.8 ± 1.5 cm/second in the group with grade 3 fatty infiltration. There was a negative inverse correlation between the grade of fatty infiltration and both VPI ( f = 55.3, p < 0.001) and MFV ( f = 43.9, p < 0.001). Conclusion The pulsatility index and mean velocity of the portal vein blood flow decrease as the severity of fatty infiltration increases. © 2008 Wiley Periodicals, Inc. J Clin Ultrasound, 2008.