Premium
Diagnostic accuracy of endometrial thickness to exclude polyps in women with postmenopausal bleeding
Author(s) -
Timmermans Anne,
Gerritse Maaike B.E.,
Opmeer Brent C.,
Jansen Frank W.,
Mol Ben W. J.,
Veersema Sebastiaan
Publication year - 2008
Publication title -
journal of clinical ultrasound
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.272
H-Index - 61
eISSN - 1097-0096
pISSN - 0091-2751
DOI - 10.1002/jcu.20415
Subject(s) - medicine , endometrial polyp , hysteroscopy , postmenopausal bleeding , carcinoma , malignancy , endometrium , radiology , uterine cavity , receiver operating characteristic , endometrial cancer , gynecology , obstetrics , uterus , cancer
Purpose To determine the accuracy of endometrial thickness measurement with transvaginal ultrasonography (TVUS) to diagnose endometrial polyps in women with postmenopausal bleeding in whom a carcinoma has been ruled out. Methods In women with postmenopausal bleeding, endometrial thickness was measured with TVUS. If endometrial thickness was >4 mm, office hysteroscopy was performed. At hysteroscopy, the uterine cavity was assessed for the presence of polyps. Patients with malignancy were excluded. We used receiver operating characteristics (ROC) analysis to assess the capacity of TVUS endometrial thickness measurement to diagnose endometrial polyps. Findings at hysteroscopy were considered to be the reference standard. Results We included 178 patients with postmenopausal bleeding and endometrial thickness >4 mm. Hysteroscopy showed an endometrial polyp in 90 patients (50%). The ROC analysis revealed that endometrial thickness had an area under the curve of 0.64 in the diagnosis of endometrial polyps. Conclusion In women with postmenopausal bleeding in whom carcinoma has been ruled out, measurement of endometrial thickness with TVUS is not useful in the diagnosis of endometrial polyps. © 2007 Wiley Periodicals, Inc. J Clin Ultrasound, 2008