Premium
Fetus with osteogenesis imperfecta presenting as increased nuchal translucency thickness in the first trimester
Author(s) -
Hsieh Charles TsungChe,
Yeh GuangPerng,
Wu HsinHung,
Wu JoungLiang,
Chou PanHsin,
Lin YuehMin
Publication year - 2008
Publication title -
journal of clinical ultrasound
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.272
H-Index - 61
eISSN - 1097-0096
pISSN - 0091-2751
DOI - 10.1002/jcu.20360
Subject(s) - medicine , osteogenesis imperfecta , first trimester , fetus , nuchal translucency , radiography , ultrasound , second trimester , obstetrics , pregnancy , surgery , radiology , anatomy , biology , genetics
Type II osteogenesis imperfecta (OI) is a perinatally lethal disorder due to type I collagen abnormalities that has been diagnosed successfully in the second trimester. We report a case of type II OI that was confirmed on postmortem histology and radiography presenting as increased nuchal translucency in the first trimester. © 2007 Wiley Periodicals, Inc. J Clin Ultrasound, 2008