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Splenic focal lesions as manifestation of sarcoidosis: Characterization with contrast‐enhanced sonography
Author(s) -
PérezGrueso María José,
Repiso Alejandro,
Gómez Rafael,
Gonzalez Concepción,
de Artaza Tomás,
Valle Julio,
García Almudena,
Carrobles Jose María
Publication year - 2007
Publication title -
journal of clinical ultrasound
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.272
H-Index - 61
eISSN - 1097-0096
pISSN - 0091-2751
DOI - 10.1002/jcu.20322
Subject(s) - medicine , sarcoidosis , nodule (geology) , pathology , radiology , contrast enhanced ultrasound , spleen , biopsy , parenchyma , ultrasound , granuloma , splenic disease , splenectomy , paleontology , biology
Abstract We report the case of a 74‐year‐old woman with elevated liver enzyme levels in whom abdominal sonographic examination revealed a diffusely heterogeneous liver parenchyma and multiple hypoechoic subcentimetric splenic nodules. Contrast‐enhanced sonography (CEUS) revealed that the splenic focal lesions did not enhance. CT examination revealed a low‐density, multinodular pattern both in the liver and in the spleen. Core biopsy of 1 hepatic nodule revealed noncaseating epithelioid cell granuloma, and the patient was diagnosed with systemic sarcoidosis. CEUS has shown to be useful in the diagnosis of focal hepatic lesions, but studies referring to splenic lesions are lacking. © 2007 Wiley Periodicals, Inc. J Clin Ultrasound, 2007