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Placental thickness in the first half of pregnancy
Author(s) -
Tongsong Theera,
Boonyanurak Pongrak
Publication year - 2004
Publication title -
journal of clinical ultrasound
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.272
H-Index - 61
eISSN - 1097-0096
pISSN - 0091-2751
DOI - 10.1002/jcu.20023
Subject(s) - medicine , nomogram , gestational age , percentile , obstetrics , gestation , confidence interval , pregnancy , placenta , fetus , ultrasound , linear regression , gynecology , statistics , radiology , mathematics , genetics , biology
Purpose This study was conducted to establish normal values of placental thickness during the first half of pregnancy. Methods Normal pregnant women with singleton pregnancies between 8 and 20 weeks of gestation were recruited into the study. All the newborns were normal at birth. Placental thickness was measured perpendicularly through the thickest part of the placenta on transabdominal scans. The placental thickness data were analyzed for mean, standard deviation, 95% confidence interval, and 2.5 th , 5 th , 50 th , 95 th , and 97.5 th percentile for each week of gestational age. The best‐fit mathematical model was derived by regression analysis. Results The total number of measurements was 333 and the number of measurements for each week of gestational age ranged from 9 to 37. Regression analysis yielded the following linear equation of the relationship: placental thickness (in mm) = gestational age (in weeks) × 1.4−5.6 (r = 0.82). Conclusion We have established a nomogram for placental thickness. This resource may be a useful aid in the early detection of placental abnormalities, such as hydropic placenta secondary to hemoglobin Bart's disease. © 2004 Wiley Periodicals, Inc. J Clin Ultrasound 32:231–234, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI: 10.1002/jcu.20023