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Effects of volume loading on left atrial systolic time intervals
Author(s) -
Okamoto Mitsunori,
Tsubokura Tokuo,
Morishita Kazuhiko,
Nakagawa Hiroshi,
Yamagata Togo,
Kawagoe Takuji,
Hondo Tatsuya,
Tsuchioka Yukiko,
Matsuura Hideo,
Kajiyama Goro
Publication year - 1991
Publication title -
journal of clinical ultrasound
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.272
H-Index - 61
eISSN - 1097-0096
pISSN - 0091-2751
DOI - 10.1002/jcu.1870190707
Subject(s) - preload , medicine , cardiology , afterload , contraction (grammar) , diastole , end diastolic volume , cardiac cycle , central venous pressure , stroke volume , blood pressure , hemodynamics , heart rate
The effects of volume loading on the left atrial preejection period (LAPEP) and left atrial ejection time (LAET) were examined in 24 patients with various heart diseases using pulsed Doppler echocardiography. In response to volume loading, the left atrial dimension before atrial contraction significantly increased from 30.6 mm ± 5.8 mm to 32.4 mm ± 5.4 mm and the change in the left atrial dimension during atrial contraction tended to increase. The peak velocity in the atrial contraction phase significantly increased from 58 cm/s ± 14 cm/s to 63 cm/s ± 13 cm/s, and the integral of the atrial contraction phase tended to increase. LAPEP significantly decreased from 114 ms ± 16 ms to 104 ms ± 14 ms and LAET significantly decreased from 128 ms ± 15 ms to 124 ± 12 ms. The relation between LAET and left ventricular end‐diastolic pressure, and that between LAPEP and mean pulmonary capillary wedge pressure, shifted downward to the right after volume loading. Thus, left atrial ejection is augmented by volume loading according to the Frank–Starling mechanism, while LAPEP decreases due to an increase in preload and LAET decreases due to an increase in afterload.