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Oligohydramnios associated with bilateral multicystic dysplastic kidneys: Prenatal diagnosis at 15 weeks' gestation
Author(s) -
Stiller Robert J,
Pinto Margarita,
Heller Charles,
Hobbins John C
Publication year - 1988
Publication title -
journal of clinical ultrasound
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.272
H-Index - 61
eISSN - 1097-0096
pISSN - 0091-2751
DOI - 10.1002/jcu.1870160613
Subject(s) - oligohydramnios , medicine , gestation , fetus , obstetrics , amniotic fluid , multicystic dysplastic kidney , pregnancy , prenatal diagnosis , kidney , genetics , biology
Lethal fetal renal malformations are invariably associated with oligohydramnios in late antennatal ultrasound examinations. Controversy exists concerning the contribution of fetal urine production to amniotic fluid volume prior to 20 weeks' gestation. We report a pregnancy complicated by maternal gold usage and fetal bilateral multicystic dysplastic kidney disease in which oligohydramnios was detected at 12 weeks' gestation. To our knowledge, no previous cases of lethal fetal renal anomalies have been made in the first trimester. The early diagnosis of fetal renal anomalies, fetal renal contribution to amniotic fluid production, and possible teratogenicity of gold therapy is discussed.