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Distal common bile duct obstruction: An experimental study in monkeys
Author(s) -
Shawker Thomas H.,
Jones Bonnie L.,
Girton Mary E.
Publication year - 1981
Publication title -
journal of clinical ultrasound
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.272
H-Index - 61
eISSN - 1097-0096
pISSN - 0091-2751
DOI - 10.1002/jcu.1870090207
Subject(s) - medicine , common bile duct , jaundice , gallbladder , biliary ducts , intrahepatic bile ducts , bile duct , bile duct diseases , biliary tract , common duct , anatomy , dilation (metric space) , gastroenterology , mathematics , combinatorics
Biliary obstruction was accomplished by surgically occluding the distal common bile duct in seven rhesus monkeys. Ultrasound scanning at 24‐hour intervals showed that dilation of the common bile duct and gallbladder occurred before elevation of bilirubin or development of jaundice. The bile ducts expanded centrifugally from the obstructing point, with dilation of the intrahepatic ducts occurring several days after the onset of obstruction. After surgical release of the obstruction, the biliary ducts contracted centripetally, with the common bile duct requiring 30–50 days to return to normal size.