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Effects of ultrasound on the prenatal development of the rat. Part 1. 3.2 MHz continuous wave at nine days of gestation
Author(s) -
Sikov Melvin R.,
Hildebrand Percy
Publication year - 1976
Publication title -
journal of clinical ultrasound
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.272
H-Index - 61
eISSN - 1097-0096
pISSN - 0091-2751
DOI - 10.1002/jcu.1870040510
Subject(s) - gestation , medicine , fetus , ultrasound , prenatal development , obstetrics , pregnancy , nuclear medicine , radiology , biology , genetics
Individual nine‐day rat embryos were exposed for 5 or 15 minutes to graded intensities of well‐characterized focused beams of 3.2 MHz continuous wave ukrasound. Fetuses were examined for effects at 20 days of gestation. Analysis of the exposure‐response relationships indicates an “apparent threshold” for prenatal mortality at 3 W/cm z (95 per cent fiducial limits 0.5‐6 W/cm 2 ). Felal size was unaffected at any exposure level and there were only a few malformations, which occured at 10.5 W/cm 2 and above.