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Prenatal sonographic diagnosis of adrenal neuroblastoma
Author(s) -
Grandó Alvaro,
Monteggía Vicente,
Gandara Carlos,
Ruano Rodrigo,
Bunduki Victor,
Zugaib Marcelo
Publication year - 2001
Publication title -
journal of clinical ultrasound
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.272
H-Index - 61
eISSN - 1097-0096
pISSN - 0091-2751
DOI - 10.1002/jcu.1029
Subject(s) - medicine , neuroblastoma , abdomen , chemotherapy , hydronephrosis , quadrant (abdomen) , metastasis , prenatal diagnosis , pregnancy , fetus , wilms' tumor , surgery , radiology , urinary system , cancer , genetics , biology , cell culture
Neuroblastoma is the most frequent extracranial solid tumor in childhood, but it is seldom diagnosed prenatally. We report a case of adrenal neuroblastoma identified at 39 weeks' menstrual age and successfully treated by postnatal surgery and chemotherapy. Sonography revealed a hyperechoic mass in the right upper quadrant of the fetal abdomen associated with hydramnios and hydronephrosis. Two days after delivery, the tumor was resected. No metastasis was identified. The infant received 6 cycles of chemotherapy, and at 2 years of age she was well, with no signs of recurrence. © 2001 John Wiley & Sons, Inc. J Clin Ultrasound 29:250–253, 2001.