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Identification and modelling of aerobic hydrolysis – application of optimal experimental design
Author(s) -
Insel Güçlü,
Orhon Derin,
Vanrolleghem Peter A
Publication year - 2003
Publication title -
journal of chemical technology and biotechnology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.64
H-Index - 117
eISSN - 1097-4660
pISSN - 0268-2575
DOI - 10.1002/jctb.807
Subject(s) - identifiability , hydrolysis , biochemical engineering , context (archaeology) , biological system , chemistry , electron acceptor , kinetics , respirometry , experimental data , process engineering , computer science , mathematics , engineering , organic chemistry , statistics , machine learning , physics , paleontology , quantum mechanics , biology
Hydrolysis mechanism plays a dominant role in the delicate balance of electron donor/electron acceptor ratios in BNR and EBPR systems as an important carbon source. In this study, the surface‐saturation‐type hydrolysis kinetics was investigated based on respirometric measurements, within the context of the theoretical and the practical identifiability of mathematical models. The identifiable parameters of a selected model were derived from respirograms. In addition, the information from the experiments was evaluated on the basis of Optimal Experimental Design (OED) methodology for different initial conditions of the batch respirometric experiment. © 2003 Society of Chemical Industry