Premium
Membranes for separation of biomacromolecules and bioparticles via flow field‐flow fractionation
Author(s) -
Kavurt Ulku Bade,
Marioli Maria,
Kok Wim Th.,
Stamatialis Dimitrios
Publication year - 2015
Publication title -
journal of chemical technology and biotechnology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.64
H-Index - 117
eISSN - 1097-4660
pISSN - 0268-2575
DOI - 10.1002/jctb.4473
Subject(s) - field flow fractionation , membrane , fractionation , flow (mathematics) , macromolecule , separation method , diffusion , membrane technology , chemistry , chromatography , mechanics , thermodynamics , physics , biochemistry
Flow field‐flow fractionation (FlFFF) is a liquid‐phase separation technique that can separate macromolecules and particles on the basis of differences in their diffusion coefficient, and therefore their size. The membrane in the FlFFF channel is one of the most important elements involved in accomplishing the separation. This mini‐review focuses on requirements and important points related to membranes used in FlFFF channels. Unless it is selected properly, the membrane can be a weak point of the technique due to risks such as sample loss because of the interactions between the sample and the membrane. © 2014 Society of Chemical Industry