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Enzymatic synthesis of ( R )‐ and ( S )‐2‐cyclohepten‐1‐ol
Author(s) -
Izumi Taeko,
Eda Yuji
Publication year - 1995
Publication title -
journal of chemical technology and biotechnology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.64
H-Index - 117
eISSN - 1097-4660
pISSN - 0268-2575
DOI - 10.1002/jctb.280620104
Subject(s) - synthon , transesterification , enantioselective synthesis , chemistry , hydrolysis , enzymatic hydrolysis , enzyme , stereochemistry , organic chemistry , catalysis
The synthetically useful chiral synthons, ( R )‐ and ( S )‐2‐cyclohepten‐1‐ol, can be prepared by an enantioselective transesterification of racemic trans ‐2‐(phenylseleno) cycloheptanol using lipases, followed by selenoxide elimination and hydrolysis.