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Preparation of spherically agglomerated crystals of the 3,5‐diglucoside of cyanidin (cyanin)
Author(s) -
Lasagabaster Aurora,
Martín Carmen,
Goñi M. Mar
Publication year - 1994
Publication title -
journal of chemical technology and biotechnology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.64
H-Index - 117
eISSN - 1097-4660
pISSN - 0268-2575
DOI - 10.1002/jctb.280600410
Subject(s) - dissolution , agglomerate , crystallization , chemical engineering , hydrochloric acid , methanol , materials science , economies of agglomeration , mother liquor , solvent , yield (engineering) , wetting , aqueous solution , chemistry , organic chemistry , composite material , metallurgy , engineering
Suitable proportions of the solvent mixture benzene:methanol:aqueous hydrochloric acid to yield the spherically agglomerated crystals of cyanin have been found. The physicochemical properties and dissolution rate of the agglomerates, in comparison with the crystals obtained by a conventional method, have been analysed. No change in the crystalline form of the basic crystals was found in acid conditions, after agglomeration. The dissolution rate of spherical agglomerates did not decrease as much as predicted from their low specific surface areas because of their improved wettability. The crystallization speed would not only avoid colour loss during the isolation and purification of anthocyanins from their natural sources, but also would increase production, save time and cost. On the other hand, a decrease in the specific surface areas will reduce powder hydroscopicity with subsequent technological and stability advantages.