Premium
Enzymatic synthesis of (R)‐ and (S)‐2‐cyclohexen‐1‐ol
Author(s) -
Izumi Taeko,
Nakamura Toshihiko,
Eda Yuji
Publication year - 1993
Publication title -
journal of chemical technology and biotechnology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.64
H-Index - 117
eISSN - 1097-4660
pISSN - 0268-2575
DOI - 10.1002/jctb.280570213
Subject(s) - synthon , transesterification , enantioselective synthesis , chemistry , cyclohexanol , organic chemistry , hydrolysis , enzymatic hydrolysis , enzyme , biocatalysis , catalysis , reaction mechanism
The synthetically useful chiral synthons ( R )‐ and ( S )2‐cyclohexen‐1‐ol can be prepared by an enantioselective transesterification of racemic trans‐2‐(phenylseleno) cyclohexanol using lipases, followed by selenoxide elimination and hydrolysis.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom