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Interaction of transport resistances with biochemical reaction in packed bed solid state fermenters: The effect of gaseous concentration gradients
Author(s) -
Gowthaman M. K.,
Ghildyal N. P.,
Rao K. S. M. S. Raghava,
Karanth N. G.
Publication year - 2007
Publication title -
journal of chemical technology and biotechnology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.64
H-Index - 117
eISSN - 1097-4660
pISSN - 0268-2575
DOI - 10.1002/jctb.280560303
Subject(s) - bioreactor , carbon dioxide , mass transfer , chemistry , aeration , packed bed , tray , volumetric flow rate , steady state (chemistry) , oxygen , chromatography , fermentation , substrate (aquarium) , analytical chemistry (journal) , thermodynamics , biochemistry , botany , physics , oceanography , organic chemistry , biology , geology
Mass transfer plays an important role in solid state fermentation (SSF) systems. Earlier work on SSF in tray bioreactors 7 indicated that steep gaseous concentration gradients developed within the substrate bed, owing to mass transfer resistances, which may adversely affect the bioreactor performance. For all practical purposes these gradients have been eliminated using a packed bed column bioreactor with forced aeration. Gaseous concentrations (oxygen and carbon dioxide) and enzyme activities were measured at various bed heights for various air flow rates during the course of fermentation. The results indicated that concentration gradients were decreased effectively by increasing air flow rate. For example, the actual oxygen and carbon dioxide concentration gradients reduced from 0.07% (v/v) cm −1 and 0.023% (v/v) cm −1 to 0.007% (v/v) cm −1 and 0.0032% (v/v) cm −1 respectively when the air flow rate was increased from 5 dm 3 min −1 to 25 dm 3 min −1 . This resulted in an overall improvement in the performance of the bioreactor in terms of enzyme production.