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Enzymatic resolution of planar chiral ferrocene derivatives
Author(s) -
Izumi Taeko,
Hino Toshimi
Publication year - 1992
Publication title -
journal of chemical technology and biotechnology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.64
H-Index - 117
eISSN - 1097-4660
pISSN - 0268-2575
DOI - 10.1002/jctb.280550404
Subject(s) - transesterification , ferrocene , trimethylsilyl , enantioselective synthesis , chemistry , resolution (logic) , organic chemistry , enantiomer , catalysis , electrode , artificial intelligence , computer science , electrochemistry
Racemic 3‐methyl, 2‐ethyl, 2‐bromo, and 2‐trimethylsilyl derivatives of formylferrocene were kinetically resolved by enantioselective reduction with a fermenting baker's yeast. Moreover, 2‐methyl, 3‐methyl, 2‐ethyl, 2‐bromo, and 2‐trimethylsilyl derivatives of hydroxymethylferrocene were optically resolved with lipases by transesterification using vinyl esters.