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Synthesis and biological activity of some 5‐substituted aminomethyl‐8‐hydroxyquinoline‐7‐sulphonic acids
Author(s) -
Yanni A. S.,
Mohharam A. M.
Publication year - 1990
Publication title -
journal of chemical technology and biotechnology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.64
H-Index - 117
eISSN - 1097-4660
pISSN - 0268-2575
DOI - 10.1002/jctb.280490305
Subject(s) - 8 hydroxyquinoline , chemistry , alkyl , aryl , organic chemistry , mannich reaction , primary (astronomy) , medicinal chemistry , combinatorial chemistry , catalysis , physics , astronomy
5‐Aryl (or alkyl)‐8‐hydroxyquinoline‐7‐sulphonic acids have been prepared by the Mannich reaction of 8‐hydroxyquinoline‐7‐sulphonic acid with primary and secondary amines. Their bactericidal activities have been determined.