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A process development for the bundling crystallization of aspartame
Author(s) -
Kishimoto Shin'ichi,
Naruse Masayoshi
Publication year - 1988
Publication title -
journal of chemical technology and biotechnology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.64
H-Index - 117
eISSN - 1097-4660
pISSN - 0268-2575
DOI - 10.1002/jctb.280430108
Subject(s) - crystallization , aspartame , supersaturation , materials science , bundle , process (computing) , scale up , chemical engineering , process engineering , crystallography , chemistry , composite material , computer science , organic chemistry , physics , engineering , biochemistry , classical mechanics , operating system
It is known that rod‐like crystals of aspartame, in which several needle crystals appear to be bundled together (bundle‐like crystals), have remarkably improved physical properties compared to the crystals obtained from a conventional stirred crystallizer. A crystallization process for obtaining bundle‐like crystals has been developed for manufacturing practice. The conditions to obtain the bundle‐like crystals are that crystallization must be carried out without stirring, with a high initial concentration of aspartame so that the amount of precipitated solid after cooling is about 10 g litre −1 or more, and with rapid cooling to produce high supersaturation. A new type of crystallizer was developed for large‐scale crystallization under these conditions. The pilot plant work was carried out in a 400‐litre crystallizer, and it has been demonstrated that the crystallization process is technically possible and economically successful in the large‐scale manufacturing of aspartame.