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Synthesis by enzymatic catalysis. IV. Transesterification of n ‐acetyl‐ L ‐tyrosine ethyl ester with α‐chymotrypsin in water—hexanol—aot micelles
Author(s) -
Testet Eric,
Baboulene Michel,
Speziale Vincent,
Lattes Armand
Publication year - 1988
Publication title -
journal of chemical technology and biotechnology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.64
H-Index - 117
eISSN - 1097-4660
pISSN - 0268-2575
DOI - 10.1002/jctb.280410109
Subject(s) - transesterification , chemistry , micelle , enzyme , yield (engineering) , hexanol , organic chemistry , catalysis , tyrosine , chymotrypsin , trypsin , biochemistry , alcohol , aqueous solution , materials science , metallurgy
A new type of microemulsion system (Aerosol‐OT, water, hexanol) was used to entrap an enzyme (α‐chymotrypsin) in a reverse micelle. N‐acetyl L ‐tyrosine ethyl ester can be solubilised in this medium to give N ‐acetyl L ‐tyrosine hexyl ester in a good yield (80%). This is the first report of a successful enzymatic transesterification in a micellar medium.