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The yeast alcohol dehydrogenase catalysed conversion of cinnamaldehyde to cinnamyl alcohol
Author(s) -
Richard Bowen W.,
Lambert Nigel,
Pug Shirley Y. R.,
Taylor Frank
Publication year - 1986
Publication title -
journal of chemical technology and biotechnology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.64
H-Index - 117
eISSN - 1097-4660
pISSN - 0268-2575
DOI - 10.1002/jctb.280360605
Subject(s) - cinnamaldehyde , cinnamyl alcohol , alcohol dehydrogenase , chemistry , cinnamyl alcohol dehydrogenase , alcohol , yeast , enzyme , biochemistry , substrate (aquarium) , alcohol oxidoreductase , organic chemistry , catalysis , biology , biosynthesis , nad+ kinase , ecology
The kinetics of the conversion of trans ‐cinnamaldehyde to trans ‐cinnamyl alcohol catalysed by yeast alcohol dehydrogenase (EC 1.1.1.1) have been characterised. Reaction with the free enzyme is curtailed after a short time as a result of inactivation by the substrate. It has been shown that immobilisation of the enzyme provides substantial protection against this inactivation. Use of the immobilised enzyme in a flow‐through reactor further enhanced the enzyme lifetime, creating a viable synthetic process. The product cinnamyl alcohol may be recovered by continuous solvent extraction.