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Reinventing HCV Treatment: Past and Future Perspectives
Author(s) -
Carter Wendy,
Connelly Sarah,
Struble Kimberly
Publication year - 2017
Publication title -
the journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.92
H-Index - 116
eISSN - 1552-4604
pISSN - 0091-2700
DOI - 10.1002/jcph.830
Subject(s) - hepatitis c virus , medicine , epidemiology , intensive care medicine , chronic hepatitis , hepatitis c , virology , hepacivirus , virus , immunology
This review paper summarizes the epidemiology of hepatitis C virus (HCV) and chronic HCV infection, including HCV virology and treatment regimens. Specifically, we focus on the evolution of past, current, and future HCV treatment options, the reasons for treatment failure, and the impact of resistance‐associated variants on treatment success.