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Dosage Adjustments Related to Young or Old Age and Organ Impairment
Author(s) -
Burris James F.,
Tortorici Michael A.,
Mandic Maja,
Neely Michael,
Reed Michael D.
Publication year - 2016
Publication title -
the journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.92
H-Index - 116
eISSN - 1552-4604
pISSN - 0091-2700
DOI - 10.1002/jcph.816
Subject(s) - medicine , intensive care medicine , pediatrics
Differences in physiology related to young or old age and/or organ system impairment alter the absorption, distribution, metabolism, and excretion of many medications and consequently their effectiveness and toxicity. This module discusses common alterations in medication use and dosage that are required in the pediatric age group, in the elderly, and in patients with renal or hepatic disease.