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How does temperature play a role in the storage of extracellular vesicles?
Author(s) -
Qin Bo,
Zhang Qi,
Hu Ximin,
Mi Tuoyang,
Yu Haiyang,
Liu Shenshen,
Zhang Bin,
Tang Mu,
Huang Jufang,
Xiong Kun
Publication year - 2020
Publication title -
journal of cellular physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.529
H-Index - 174
eISSN - 1097-4652
pISSN - 0021-9541
DOI - 10.1002/jcp.29700
Subject(s) - extracellular vesicles , nucleic acid , microvesicles , function (biology) , vesicle , microbiology and biotechnology , nanotechnology , biochemical engineering , chemistry , biology , biochemistry , microrna , materials science , engineering , membrane , gene
Extracellular vesicles (EVs) contain specific proteins, lipids, and nucleic acids that can be passed to other cells as signal molecules to alter their function. However, there are many problems and challenges in the conversion and clinical application of EVs. Storage and protection of EVs is one of the issues that need further research. To adapt to potential clinical applications, this type of problem must be solved. This review summarizes the storage practices of EVs in recent years, and explains the impact of temperature on the quality and stability of EVs during storage based on current research, and explains the potential mechanisms involved in this effect as much as possible.