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Hypolipidemic effects of Rosmarinus officinalis L
Author(s) -
Farkhondeh Tahereh,
Samarghandian Saeed,
PourbagherShahri Ali Mohammad
Publication year - 2019
Publication title -
journal of cellular physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.529
H-Index - 174
eISSN - 1097-4652
pISSN - 0021-9541
DOI - 10.1002/jcp.28221
Subject(s) - dyslipidemia , rosmarinus , officinalis , medicine , traditional medicine , oxidative stress , pharmacology , obesity
Dyslipidemia is one of the major risk factors for cardiovascular diseases (CVDs). Current strategies are not effective in the management of dyslipidemia. Thus, there is a necessity to find new preventative and therapeutic approaches. In recent years, herbal medicine has drawn great attention regarding the prevention and management of dyslipidemia. Rosmarinus officinalis , commonly known as rosemary, is an evergreen shrub containing several polyphenols. The plant grows in the Mediterranean and South American regions. Rosemary and its main components have antioxidant, anti‐inflammatory, and lipid‐lowering properties. The present review has focused on in vivo and in vitro studies on the hypolipidemic effects of rosemary and its main constituents as well as their functional mechanisms. Studies have described lipid‐scavenging activities of rosemary through its avonoid contents. Modulating inflammation and oxidative stress have been described as possible mechanisms by which rosemary ameliorates dyslipidemia. However, the exact mechanisms are not fully understood yet. Conducting experimental and clinical trial studies are recommended to conrm the safety and efficacy of rosemary in the prevention and management of dyslipidemia and other cardio‐metabolic diseases.