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The immunomodulatory role of probiotics in allergy therapy
Author(s) -
Hajavi Jafar,
Esmaeili SeyedAlireza,
Varasteh AbdolReza,
Vazini Hossein,
Atabati Hadi,
Mardani Fatemeh,
MomtaziBorojeni Amir A.,
Hashemi Maryam,
Sankian Mojtaba,
Sahebkar Amirhossein
Publication year - 2019
Publication title -
journal of cellular physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.529
H-Index - 174
eISSN - 1097-4652
pISSN - 0021-9541
DOI - 10.1002/jcp.27263
Subject(s) - allergy , probiotic , immune system , immunology , medicine , disease , incidence (geometry) , food allergy , intensive care medicine , biology , bacteria , genetics , physics , optics
The increased incidence of allergic disorders may be the result of a relative fall in microbial induction in the intestinal immune system during infancy and early childhood. Probiotics have recently been proposed as viable microorganisms for the prevention and treatment of specic allergic diseases. Different mechanisms have been considered for this probiotic property, such as generation of cytokines from activated pro‐T‐helper type 1 after bacterial contact. However, the effects of its immunomodulatory potential require validation for clinical applications. This review will focus on the currently available data on the benefits of probiotics in allergy disease.