Premium
Interplay between miRNAs and human diseases
Author(s) -
Paul Prosenjit,
Chakraborty Anindya,
Sarkar Debasree,
Langthasa Malobika,
Rahman Musfhia,
Bari Minakshi,
Singha RK. Sanamacha,
Malakar Arup Kumar,
Chakraborty Supriyo
Publication year - 2018
Publication title -
journal of cellular physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.529
H-Index - 174
eISSN - 1097-4652
pISSN - 0021-9541
DOI - 10.1002/jcp.25854
Subject(s) - microrna , disease , biology , bioinformatics , computational biology , cancer , gene , medicine , genetics , pathology
MicroRNAs (miRNAs) are endogenous, non‐coding RNAs, which have evoked a great deal of interest due to their importance in many aspects of homeostasis and diseases. MicroRNAs are stable and are essential components of gene regulatory networks. They play a crucial role in healthy individuals and their dysregulations have also been implicated in a wide range of diseases, including diabetes, cardiovascular disease, kidney disease, and cancer. This review summarized the current understanding of interactions between miRNAs and different diseases and their role in disease diagnosis and therapy.