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Proteomics Applications in Dental Derived Stem Cells
Author(s) -
Li Jie,
Tian Weidong,
Song Jinlin
Publication year - 2017
Publication title -
journal of cellular physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.529
H-Index - 174
eISSN - 1097-4652
pISSN - 0021-9541
DOI - 10.1002/jcp.25667
Subject(s) - stem cell , proteomics , proteome , context (archaeology) , microbiology and biotechnology , regeneration (biology) , biology , computational biology , bioinformatics , biochemistry , gene , paleontology
At present, the existence of a variety of dental derived stem cells has been documented. These cells displayed promising clinical application potential not only for teeth and its surrounding tissue regeneration, but also for other tissues, such as nerve and bone regeneration. Proteomics is an unbiased, global informatics tool that provides information on all protein expression levels as well as post‐translational modification in cells or tissues and is applicable to dental derived stem cells research. Over the last decade, considerable progress has been made to study the global proteome, secrotome, and membrane proteome of dental derived stem cells. Here, we present an overview of the proteomics studies in the context of stem cell research. Particular attention is given to dental derived stem cell types as well as current challenges and opportunities. J. Cell. Physiol. 232: 1602–1610, 2017. © 2016 Wiley Periodicals, Inc.