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MDA‐9/Syntenin Control
Author(s) -
Philley Julie V.,
Kannan Anbarasu,
Dasgupta Santanu
Publication year - 2016
Publication title -
journal of cellular physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.529
H-Index - 174
eISSN - 1097-4652
pISSN - 0021-9541
DOI - 10.1002/jcp.25136
Subject(s) - control (management) , business , environmental science , chemistry , computer science , artificial intelligence
MDA‐9/Syntenin is a small PDZ domain containing scaffolding protein with diverse array of functions regulating membrane trafficking, cell adhesion, neural, and synaptic development, ubiquitination, and exosome biogenesis. An appreciable number of studies also established a pivotal role of MDA‐9/Syntenin in cancer development and progression. In this review, we will discuss the dynamic role of MDA‐9/Syntenin in regulating normal and abnormal fate of various cellular processes. J. Cell. Physiol. 231: 545–550, 2016. © 2015 Wiley Periodicals, Inc.