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The role of mitochondrial derived peptides (MDPs) in metabolism
Author(s) -
Alis Rafael,
Lucia Alejandro,
Blesa Jose R,
SanchisGomar Fabian
Publication year - 2015
Publication title -
journal of cellular physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.529
H-Index - 174
eISSN - 1097-4652
pISSN - 0021-9541
DOI - 10.1002/jcp.25023
Subject(s) - valencia , humanities , art , biology , ecology
The term "mitokines" refers to signals derived from mitochondria that have an impact on other cells or tissues (Durieux et al., 2011). Rather than being simply a set of DNA composed by 37 genes, the mitochondrial DNA (mtDNA) is quite complex and includes small RNAs (Mercer et al., 2011). Mitochondrial-derived peptides (MDPs) are encoded by functional short open reading frames (sORFs) in the mtDNA.4.155 JCR (2015) Q1, 12/83 Physiology; Q2, 63/187 Cell biologyUE
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