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The science of stem cell biobanking: Investing in the future
Author(s) -
Diaferia Giuseppe R.,
Cardano Marina,
Cattaneo Monica,
Spinelli Chiara C.,
Dessì Sara S.,
DeBlasio Pasquale,
Biunno Ida
Publication year - 2012
Publication title -
journal of cellular physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.529
H-Index - 174
eISSN - 1097-4652
pISSN - 0021-9541
DOI - 10.1002/jcp.22732
Subject(s) - stem cell , pace , biobank , drug discovery , quality (philosophy) , business , biology , computer science , computational biology , microbiology and biotechnology , bioinformatics , geography , epistemology , philosophy , geodesy
Abstract The use of human stem cells in biomedical research projects is increasing steadily and the number of cells that are being derived develops at a remarkable pace. However, stem cells around the world are vastly different in their provenance, programming, and potentials. Furthermore, knowledge on the actual number of cell types, their derivation, availability, and characteristics is rather sparse. Usually, “colleague‐supply” avenues constantly furnish cells to laboratories around the world without ensuring their correct identity, characterization, and quality. These parameters are critical if the cells will be eventually used in toxicology studies and drug discovery. Here, we outline some basic principles in establishing a stem cell‐specific bank. J. Cell. Physiol. 227: 14–19, 2012. © 2011 Wiley Periodicals, Inc.