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Magic spot: (p) ppGpp
Author(s) -
Wu Jun,
Xie Jianping
Publication year - 2009
Publication title -
journal of cellular physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.529
H-Index - 174
eISSN - 1097-4652
pISSN - 0021-9541
DOI - 10.1002/jcp.21797
Subject(s) - stringent response , guanosine , bacteria , gene , transcription (linguistics) , nucleic acid , regulator , biology , biochemistry , chemistry , microbiology and biotechnology , genetics , escherichia coli , linguistics , philosophy
Guanosine 5′‐(tri)diphosphate, 3′‐diphosphate [(p) ppGpp] is a small nucleic acid that helps bacteria survive in limited environments. Gene chip shows that (p) ppGpp is a global transcription‐regulator of genes related to important bacterial metabolic processes. Therefore, more attention should be focused on the molecular mechanisms of (p) ppGpp, as it is the foundation to understanding how bacteria adapt to extreme circumstances through the stringent response. J. Cell. Physiol. 220: 297–302, 2009. © 2009 Wiley‐Liss, Inc.