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Lessons learned from art pardee in cell cycle, science, and life
Author(s) -
Dou Q. Ping
Publication year - 2006
Publication title -
journal of cellular physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.529
H-Index - 174
eISSN - 1097-4652
pISSN - 0021-9541
DOI - 10.1002/jcp.20800
Subject(s) - honor , proteasome , cell cycle , cancer research , cell , biology , microbiology and biotechnology , computer science , genetics , operating system
Abstract This essay is written to honor Dr Art Pardee's 85th birthday (July 13, 2006). In this essay, I have summarized the lessons I learned from Art and the cell‐cycle research I performed in Art's laboratory during my postdoctoral training period. I have also summarized some research from my own laboratory that has been inspired by the lessons I learned from Art, including the interactions between cell cycle and cell death regulators and discovery of novel polyphenol‐ and copper‐based proteasome inhibitors. Finally, I have discussed the potential use of these proteasome inhibitors in cancer prevention and treatment. J. Cell. Physiol. 209: 663–669, 2006. © 2006 Wiley‐Liss, Inc.