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Characterization of chloride uptake in Drosophila Kc cells
Author(s) -
Sherwood Ann C.,
JohnAlder Kathleen,
Sanders Marilyn M.
Publication year - 1988
Publication title -
journal of cellular physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.529
H-Index - 174
eISSN - 1097-4652
pISSN - 0021-9541
DOI - 10.1002/jcp.1041360315
Subject(s) - vanadate , chloride , chemistry , nitrate , biophysics , drosophila (subgenus) , biochemistry , biology , organic chemistry , gene
Drosophila Kc cells use at least two mechanisms for chloride uptake. These transport systems can be distinguished by their kinetic properties and by their differential sensitivity to various drugs. One transport system predominates at [Cl − ] 0 below 30 mM and is greater than fivefold more sensitive to disulfonic stilbenes than the second system. At [Cl − ] 0 above 30 mM, the predominant uptake mechanism is inhibited by vanadate and nitrate.