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In vitro differentiation of F‐9 teratocarcinoma cells does not induce expression of endogenous retroviral glycoprotein
Author(s) -
Schmidt Martin,
Horak Ivan,
Wecker Eberhard
Publication year - 1982
Publication title -
journal of cellular physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.529
H-Index - 174
eISSN - 1097-4652
pISSN - 0021-9541
DOI - 10.1002/jcp.1041130514
Subject(s) - endogeny , teratocarcinoma , biology , in vitro , endogenous retrovirus , glycoprotein , microbiology and biotechnology , cellular differentiation , context (archaeology) , cell culture , antigen , genetics , gene , biochemistry , genome , paleontology
Undifferentiated F‐9 Teratocarcinoma cells derived from 129/j mice are induced in vitro to express several differentiation markers. Neither undifferentiated nor differentiated F‐9 cells express endogenous retroviral glycoprotein (gp70), although the latter can be productively infected with exogenous retroviruses. This is discussed in context with previous findings that all antigen‐activated lymphocytes of all mice express endogenous retroviral gp70.