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A survey of intracellular Na + and K + of various normal, transformed, and tumor cells
Author(s) -
Moyer Mary Pat,
Mover Rex C.,
Waite Marilynn R. F.
Publication year - 1982
Publication title -
journal of cellular physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.529
H-Index - 174
eISSN - 1097-4652
pISSN - 0021-9541
DOI - 10.1002/jcp.1041130121
Subject(s) - intracellular , tumor cells , transformation (genetics) , absorption (acoustics) , chemistry , atomic absorption spectroscopy , cell , microbiology and biotechnology , biochemistry , biology , physics , cancer research , optics , gene , quantum mechanics
Intracellular concentrations of Na + and K + of various normal, transformed, and tumor cell cultures were analyzed by atomic absorption spectrophotometry. In all of the cultures analyzed there were markedly different concentrations in the transformed and tumor cells when compared to their normal counterparts. Although increased Na + was often observed, there were no definitive correlations between absolute ion concentrations, or Na + :K + ratios, and cell transformation.