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Effect of cocultivation of the levels of spontaneous and induced sister chromatid exchanges in chinese hamster cells
Author(s) -
Rainaldi Giuseppe,
Luccini Fulvio,
Mariani Tullio
Publication year - 1982
Publication title -
journal of cellular physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.529
H-Index - 174
eISSN - 1097-4652
pISSN - 0021-9541
DOI - 10.1002/jcp.1041120218
Subject(s) - sister chromatids , chinese hamster , sister chromatid exchange , hamster , genetics , chemistry , microbiology and biotechnology , biology , dna , gene , chromosome
The level of sister chromatid exchanges, both spontaneous and induced by UV light or ethylmethanesulphonate (EMS), in Chinese hamster V79/AP4 cell line, is partially reduced upon cocultivation with human cells. Normal and xeroderma pigmentosum (XP) cells are equally effective. On the basis of these observations, cocultivation may represent a good tool for investigating the SCE's formation processes.