Effect of cocultivation of the levels of spontaneous and induced sister chromatid exchanges in chinese hamster cells | Zendy

Rainaldi Giuseppe | Zendy; Luccini Fulvio | Zendy; Mariani Tullio | Zendy

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Effect of cocultivation of the levels of spontaneous and induced sister chromatid exchanges in chinese hamster cells

Author(s) -

Rainaldi Giuseppe,

Luccini Fulvio,

Mariani Tullio

Publication year - 1982

Publication title -

journal of cellular physiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.529

H-Index - 174

eISSN - 1097-4652

pISSN - 0021-9541

DOI - 10.1002/jcp.1041120218

Subject(s) - sister chromatids , chinese hamster , sister chromatid exchange , hamster , genetics , chemistry , microbiology and biotechnology , biology , dna , gene , chromosome

The level of sister chromatid exchanges, both spontaneous and induced by UV light or ethylmethanesulphonate (EMS), in Chinese hamster V79/AP4 cell line, is partially reduced upon cocultivation with human cells. Normal and xeroderma pigmentosum (XP) cells are equally effective. On the basis of these observations, cocultivation may represent a good tool for investigating the SCE's formation processes.

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