Concanavalin A induces an intraluminal alkalinization of thymocyte membrane vesicles | Zendy

Mikkelsen Ross B. | Zendy; SchmidtUllrich Rupert | Zendy; Wallach Donald F. H. | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Concanavalin A induces an intraluminal alkalinization of thymocyte membrane vesicles

Author(s) -

Mikkelsen Ross B.,

SchmidtUllrich Rupert,

Wallach Donald F. H.

Publication year - 1980

Publication title -

journal of cellular physiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.529

H-Index - 174

eISSN - 1097-4652

pISSN - 0021-9541

DOI - 10.1002/jcp.1041020203

Subject(s) - concanavalin a , vesicle , thymocyte , membrane , reagent , biophysics , chemistry , biochemistry , biology , microbiology and biotechnology , immunology , in vitro , immune system , t cell

Weak acid distribution methods demonstrate that mitogenic levels of concanavalin A induce an intravesicular alkalinization of isolated thymocyte membrane vesicles. Experiments with chemical reagents that crosslink the high affinity concanavalin A receptor and extensive correlation with known cellular events suggest that a “membrane Bohr effect” may participate in the initiation of mitogenesis.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research