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Potentiation by p ‐fluorophenylalanine of the division‐delaying effects of high hydrostatic pressure in synchronized Tetrahymena pyriformis
Author(s) -
Walker Eric,
Wheatley Denys N.
Publication year - 1979
Publication title -
journal of cellular physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.529
H-Index - 174
eISSN - 1097-4652
pISSN - 0021-9541
DOI - 10.1002/jcp.1041010307
Subject(s) - tetrahymena pyriformis , tetrahymena , division (mathematics) , hydrostatic pressure , hydrostatic equilibrium , cell division , long term potentiation , biology , microbiology and biotechnology , cell , genetics , mathematics , physics , mechanics , arithmetic , quantum mechanics , receptor
Cultures of heat‐synchronized Tetrahymena pyriformis , growing in a proteose peptone medium, were subjected to short pulses of the amino acid analogue, p ‐flurophenylalanine, and high hydrostatic pressure. The pulses of these agents were chosen so that, when applied individually, they did not appreciably delay cell division. However, combined treatments, analogue pulse followed by pressure pulse, produced a pronounced synergism. The results are interpreted as further evidence to support the inclusion of analogue division proteins in pressure labile assemblies during the progression of Tetrahymena into division.