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Effect of 5‐bromodeoxyuridine on incorporation of RNA precursors in sea urchin embryos
Author(s) -
Fitzmaurice Leona C.,
Baker Robert F.
Publication year - 1974
Publication title -
journal of cellular physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.529
H-Index - 174
eISSN - 1097-4652
pISSN - 0021-9541
DOI - 10.1002/jcp.1040830212
Subject(s) - bromodeoxyuridine , embryo , sea urchin , rna , biology , dna , uridine , microbiology and biotechnology , andrology , biochemistry , chemistry , cell growth , gene , medicine
Exposure of early sea urchin embryos to 5‐bromodeoxyuridine (at concentrations up to 100 μg per ml) severely decreases the uptake of exogenous 3 H‐uridine into RNA. However, the actual gross rate of DNA or RNA synthesis in these embryos appears not to be affected by the presence of 5‐bromodeoxyuridine.