A melanin‐dispersing effect of cyclic adenosine monophosphate on  Fundulus  melanophores | Zendy

Novales R. R. | Zendy; Fujii R. | Zendy

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A melanin‐dispersing effect of cyclic adenosine monophosphate on Fundulus melanophores

Author(s) -

Novales R. R.,

Fujii R.

Publication year - 1970

Publication title -

journal of cellular physiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.529

H-Index - 174

eISSN - 1097-4652

pISSN - 0021-9541

DOI - 10.1002/jcp.1040750116

Subject(s) - chromatophore , adenosine , fundulus , adenosine monophosphate , melanophore , melanin , chemistry , cyclic adenosine monophosphate , medicine , endocrinology , biology , biochemistry , genetics , receptor , fishery , fish <actinopterygii>

Treatment of Fundulus melanophores with adenosine 3′,5′‐monophosphate (cyclic AMP) is followed by reversible melanin dispersion in these cells. Adenosine 3′‐monophosphate and adenosine 5′‐monophosphate both have a similar, but weaker dispersing action. In addition, adenosine 5′‐monophosphate also has a melanin aggregating effect. These results are interpreted to mean that nerve transmitters may act by controlling the level of cyclic AMP within the Fundulus melanophore.

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