Premium
Evidence for dual physiological forms of ergosterol in Saccharomyces cerevisiae
Author(s) -
Adams B. G.,
Parks L. W.
Publication year - 1967
Publication title -
journal of cellular physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.529
H-Index - 174
eISSN - 1097-4652
pISSN - 0021-9541
DOI - 10.1002/jcp.1040700205
Subject(s) - ergosterol , saponification , sterol , yeast , saccharomyces cerevisiae , biochemistry , chemistry , hydrolysis , biology , cholesterol
Data obtained from acid hydrolysis and extraction of yeast have demonstrated that routine saponification does not recover total sterol from the cells. This suggests the existence of a form of ergosterol resistant to saponification. Time course analyses of sterol synthesis by resting cell suspensions reveal an inverse relationship between the amounts of base labile and acid labile forms of sterol. These data give strong presumptive evidence for dual forms of ergosterol which are interconvertible according to the respiratory state of the cell.