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An effect of exogenous thymidine on the cell cycle in Haplopappus gracilis
Author(s) -
Ames Ira H.,
Mitra Jyotirmay
Publication year - 1967
Publication title -
journal of cellular physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.529
H-Index - 174
eISSN - 1097-4652
pISSN - 0021-9541
DOI - 10.1002/jcp.1040690216
Subject(s) - thymidine , mitosis , meristem , metaphase , mitotic index , cell division , cell cycle , chemistry , biology , microbiology and biotechnology , cell , biochemistry , dna , chromosome , gene
Abstract The study of an effect of exogenous thymidine on the mitotic cycle demonstrated that a 30 minute exposure to unlabeled and to tritiated thymidine at a concentration of 2.9 × 10 −6 M was sufficient to cause a significant increase in the mitotic index of root meristem cells of Haplopappus gracilis . An analysis of the data revealed that this was due to the prolongation of metaphase rather than to an increase in the actual number of cells entering division.