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Heat shock proteins and the pancreas
Author(s) -
Rakonczay Zoltán,
Takács Tamás,
Boros Imre,
Lonovics János
Publication year - 2003
Publication title -
journal of cellular physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.529
H-Index - 174
eISSN - 1097-4652
pISSN - 0021-9541
DOI - 10.1002/jcp.10268
Subject(s) - heat shock protein , acute pancreatitis , microbiology and biotechnology , shock (circulatory) , function (biology) , biology , heat shock , pancreatitis , pancreas , medicine , biochemistry , gene
Heat shock proteins (HSPs) are cytoprotective molecules that help to maintain the metabolic and structural integrity of cells. In this review, we briefly discuss the regulation and function of HSPs. The review focuses on the current knowledge of pancreatic HSP induction, the HSP level changes during acute pancreatitis, the potential effects of the pre‐ and co‐induction of HSPs in experimental acute pancreatitis, and the mechanisms by which HSPs might mediate cellular protection. © 2003 Wiley‐Liss, Inc.